Breast cancer is an uncontrolled growth of breast cells. To better understand breast cancer, it helps to understand how any cancer can develop.
Cancer occurs as a result of mutations, or abnormal changes, in the genes responsible for regulating the growth of cells and keeping them healthy. The genes are in each cell’s nucleus, which acts as the “control room” of each cell. Normally, the cells in our bodies replace themselves through an orderly process of cell growth: healthy new cells take over as old ones die out. But over time, mutations can “turn on” certain genes and “turn off” others in a cell. That changed cell gains the ability to keep dividing without control or order, producing more cells just like it and forming a tumor.
A tumor can be benign (not dangerous to health) or malignant (has the potential to be dangerous). Benign tumors are not considered cancerous: their cells are close to normal in appearance, they grow slowly, and they do not invade nearby tissues or spread to other parts of the body. Malignant tumors are cancerous. Left unchecked, malignant cells eventually can spread beyond the original tumor to other parts of the body.
The term “breast cancer” refers to a malignant tumor that has developed from cells in the breast. Usually breast cancer either begins in the cells of the lobules, which are the milk-producing glands, or the ducts, the passages that drain milk from the lobules to the nipple. Less commonly, breast cancer can begin in the stromal tissues, which include the fatty and fibrous connective tissues of the breast.
Over time, cancer cells can invade nearby healthy breast tissue and make their way into the underarm lymph nodes, small organs that filter out foreign substances in the body. If cancer cells get into the lymph nodes, they then have a pathway into other parts of the body. The breast cancer’s stage refers to how far the cancer cells have spread beyond the original tumor.
Breast cancer is always caused by a genetic abnormality (a “mistake” in the genetic material). However, only 5-10% of cancers are due to an abnormality inherited from your mother or father. About 90% of breast cancers are due to genetic abnormalities that happen as a result of the aging process and the “wear and tear” of life in general.
There are steps every person can take to help the body stay as healthy as possible and lower risk of breast cancer or a breast cancer recurrence (such as maintaining a healthy weight, not smoking, limiting alcohol, and exercising regularly). Learn what you can do to manage breast cancer risk factors. Always remember, breast cancer is never anyone’s fault. Feeling guilty, or telling yourself that breast cancer happened because of something you or anyone else did, is not productive.
From the National Cancer Institute the estimated new cases and deaths from breast cancer in the United States in 2011 were:
- New Cases: 230,480 (female); 2,140 (male)
- Deaths: 39,520(female); 450 (male)
The purpose of our site is to collect resources together for those interested in learning more about breast cancer and serve as an additional source of links to authoritative infomation.
Breast Cancer Resources
The Department of Health and Human Services and the Center for Disease Control and Prevention contains many useful resources for those interested in learning about breast cancer, breast cancer prevention, and the ongoing efforts to find a cure for breast cancer. To learn more, please visit their site at http://apps.nccd.cdc.gov/cancercontacts/nbccedp/contacts.asp.
The National Cancer Institute as part of the National Institutes of Health has a very informative site that contains many resources and information about treatment options, clinical trials, cancer literature, stastics, and research and related information. To learn more, please visit their site at http://www.cancer.gov/cancertopics/types/breast.